Browsing by Subject "Drug repurposing"
Now showing items 1-11 of 11
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A comprehensive review on drug repurposing in cancer treatment
(Brac University, 2023-08)Cancer, a complex and highly detrimental group of medical conditions, continues to become a significant global health burden. Despite oncology research's advances, cancer drug development has fallen behind due to a number ... -
Drug Repurposing : search for a drug having effective anticancer activity
(BRAC University, 2017-07-26)In search of finding better and safer drugs and due to the high cost and decreasing productivity of novel drug discovery programs, scientists are now becoming more interested in finding new therapeutic indications for the ... -
Drug repurposing in NCDs: benefits and challenges
(Brac University, 2021-04)This review focuses on repurposing of drugs for the treatment of noncommunicable diseases. Drug repurposing is the development of new indications for existing drugs. Noncommunicable diseases are causing large number of ... -
Drug repurposing: potential of Antimicrobial Drugs in Breast Cancer Treatment
(Brac University, 2023-08)Researchers and doctors have been encouraged to repurpose currently used medications to lessen the financial burden of drug development and provide potential novel treatments because of the rising expense of drugs globally, ... -
Drug repurposing: search for targeted drug candidates in the treatment of HER2 positive breast cancer
(Brac University, 2023-09)According to GLOBOCAN data, 2020, breast cancer (BC) is the leading cause of cancer-related mortalities worldwide, with HER2 positive breast cancer being very prevalent. The rising incidence of HER2 positive breast cancer ... -
Evolution of Superbugs: a lethal bioterror
(Brac University, 2019-10)Over the past few decades, the increasing rate of antibiotic resistance (ABR) has led to the emergence of superbugs, a group of deadly pathogens with antibiotic resistance in their supreme level. About two million people ... -
Molecular docking of Fluvastatin and Teneligliptin targeting AT1R in hypertension
(Brac University, 2019-05)Hypertension, or high blood pressure is a major risk factor causing cardiovascular diseases such as cerebrovascular stroke and ischemic heart disease. It is now considered as one of the most common disease and over 1.13 ... -
A review on drug repurposing for diabetes epidemic
(Brac University, 2021-09)Repurposing of existing drugs to treat chronic, communicable and non-communicable diseases is becoming progressively important since it uses existing drug molecules or failed compounds by utilizing the available data. It ... -
A review on potential anticancer properties of antidiabetic drugs: metformin and sulfonylureas
(Brac University, 2024-02)Diabetes mellitus is a public health emergency that is increasing drastically worldwide. In many research findings, it is shown that it causes not only cardiovascular diseases but also increases the risk of cancer. Metformin ... -
A review on the potential of repurposing of metformin for colon cancer and breast cancer
(BRAC University, 2023-02)Metformin, a hypoglycemic agent is currently being repurposed for the treatment of different types of cancer due to its pleiotropic functions, affordability, stability at room temperature with long shelf life, broadly ... -
Use of combination of satins as antagonists of SPARC in stomach cancer: an in silico study
(Brac University, 2019-05)SPARC is a protein found in gastric cell line. It has a dual role of tumor suppression and tumor progression. Over expression of SPARC in gastric cell line can lead to Stomach / Gastric cancer which is one of the leading ...
