Browsing by Subject "Cancer--Treatment"
Now showing items 1-20 of 25
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Biosimilar in lymphoma treatment
(Brac University, 2021-04)We are living in an era where the number of ageing population is increasing, as well as the demand for treating chronic conditions like cancer, cardiovascular disease, diabetes, etc. Considering the different types of ... -
Comparing effectiveness and safety of combination therapy for esophageal and gastro esophageal junction cancer: a comprehensive meta-analysis
(Brac University, 2023-12)Introduction: In cases of resectable esophageal cancer, neoadjuvant immune checkpoint inhibitors and chemotherapy have been examined. Nonetheless, conflicting findings have been found in subsequent research. Thus, meta-analysis ... -
A comprehensive bioinformatics analysis of BRAF in cancer
(Brac University, 2021-09)BRAF is one of the most vital serine/ threonine-protein kinase proto-oncogenes that performs a crucial role in cellular proliferation, growth, signaling and secretion. By deregulation of this gene can lead to terrible ... -
A comprehensive review on drug repurposing in cancer treatment
(Brac University, 2023-08)Cancer, a complex and highly detrimental group of medical conditions, continues to become a significant global health burden. Despite oncology research's advances, cancer drug development has fallen behind due to a number ... -
CRISPR: a revolutionary tool for modeling and treating cancer and Duchenne muscular dystrophy
(Brac University, 2022-04)The novel CRISPR/Cas system is an effective and widely used gene-editing tool that has created the opportunity to study gene function and understand the pathogenic mechanisms underlying various genetic disorders. It has ... -
Current practice and approaches of immunotherapy in Cancer treatment
(Brac University, 2021-09)Cancer has been and continues to be one of the leading causes of human deaths. Thousands lose their lives to the different types of cancer each year. Cancer remains one of those invincible barriers in the health sector ... -
An examination of therapeutic synergy: a comprehensive meta-analysis comparing the efficacy of TAS-102 and FOLFOX as a combination therapy for colon cancer
(Brac University, 2024-02)The treatment of colon cancer is a major healthcare issue that requires exploration of several treatment approaches. With an emphasis on overall survival, progression-free survival, and adverse events, this meta-analysis ... -
Immunotherapy in the Management of Lung Cancer
(Brac University, 2021-11)Among all the major cancer types, lung cancer is one of the most common as it holds a higher percentage of cancer related mortality and treating lung cancer is yet a challenge. Chemotherapy, radiation therapy, surgery ... -
The impact of cell penetrating peptides in prospective cancer therapy: a review
(Brac University, 2023-02)Cell penetrating peptides have been identified as a viable tool for therapeutic use in the era of biomedicines and specialized carrier systems. Similar to other therapeutic peptides, peptide stability- the bottleneck for ... -
Oncolytic viral therapy: new horizons for cancer remedy in the 21st Century
(Brac University, 2019-08)Oncolytic viral therapy has proven to be propitious that is making glorious inroads against the vicious claws of cancer. Oncolytic viruses (OVs) are modified to replicate in a selective manner in neoplastic cells. They ... -
Precision medicine in four deadliest Cancers of the world : present practices & future prospects
(Brac University, 2022-02)Cancer is a very personalized disease which is why conventional oncology treatment following the ‘one size fits all’ method is unable to cure all patients effectively and for this, cancer remains one of the leading causes ... -
Prevalence and application of an evolving genome editing tool “CRISPR/Cas System” in cancer research and treatment
(Brac University, 2022-12)One of the biggest causes of mortality worldwide is cancer. Cancer is one of the most challenging diseases to cure because of its capacity to spread quickly, metastasis, and create diverse tumors as a result of mutagenesis ... -
Recent advances in Cancer treatment targeting autophagy and future aspects
(Brac University, 2022-03)Lysosomal autophagy controls cellular homeostasis by degrading and recycling cytoplasmic molecules and organelles in the lysosome. This process in neuronal cells protects cognitive decline by removing abnormal intracellular ... -
A review of endocannabinoid system and its pharmacological role as a drug target for cancer therapies
(Brac University, 2023-02)Cancer is a genetic disorder that causes uncontrolled cell proliferation and the cells are unable to maintain apoptosis which leads the cells to cross their natural boundaries. Treatment of this diseases requires a complex ... -
A review on Bruton's Tyrosine Kinase inhibitors to outline the scopes of further advancements in the treatment of cancer
(Brac University, 2023)In many B cell malignancies, Bruton's tyrosine kinase (BTK), a non-receptor kinase, plays a significant role in oncogenic signaling that is essential for the proliferation and survival of leukemic cells. BTK works as a ... -
A review on nanoparticles based drug delivery in cancer treatment: advantages & challenges
(Brac University, 2022-06)Nanoparticles have unique physicochemical and biological properties that make them one of the most promising candidate for targeted cancer therapy. Nanoparticle-based drug delivery has a number of advantages over conventional ... -
A review on non-polyphenolic and terpenoid phytoconstituents with antioxidant and cytotoxic potential
(Brac University, 2020-03)Plants with antioxidant and cytotoxic activity possess wide number of different phytoconstituents such as tocopherol, polyphenolic compounds, flavonoids, ascorbic acid etc. However, plants having non-polyphenolic compounds ... -
A review on potential of PARP inhibitors in the treatment of prostate cancer
(Brac University, 2022-05)Prostate cancer is still a fatal disease at metastatic castration resistance stage (mCRPC) in spite of pursuing advancements in patient survival, indicating the necessity of therapeutic approaches. A significant number of ... -
A review paper on iron oxide nanoparticle based strategies in cancer treatment
(Brac University, 2022-11)The advanced approach of magnetic iron oxide nanoparticles (IONs) offers new opportunities in the field of diagnosing life-threatening diseases including cancer treatment. Due to their superior magnetic anisotropy, ... -
A review paper on Nanotechnology based strategies in the treatment of cancer
(Brac University, 2022-02)Nanotechnology is a new discipline meeting the requirement for novel methods in cancer treatment. Recently, cancer became very fatal condition that causes death worldwide. Hence, traditional cancer treatment like ...