Browsing by Subject "Bioinformatics"
Now showing items 1-10 of 10
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Bioinformatics and machine learning in prevention, detection and treatment of HIV/AIDS
(Brac University, 2021-07)As the acquired immunodeficiency syndrome (AIDS) pandemic continues to be a major health crisis of global concern, new strategies in the management and treatment of the disease is being explored. This project titled ... -
A computational approach to design putative potential siRNAs for silencing the nucleoprotein and surface glycoprotein gene of MARV
(Brac University, 2023-06)Marburg virus (MARV), a member of the Filoviridae family, is the causal agent of a highly fatal hemorrhagic fever with mortality rates ranging from 23% to 90% in humans. This virus is endemic to central Africa and leads ... -
Developing a machine learning based prognostic model and a supporting web-based application for predicting the possibility of early diabetes and diabetic kidney disease
(Brac University, 2021-06)Machine Learning has gotten attention in the healthcare industry for the competences to ameliorate disease prediction. Machine learning has already been used in the health sector. Diabetes can also trigger the permanent ... -
Finding motifs from DNA sequence using heuristic approach
(Brac University, 2021-01)Finding patterns of the short sequences in DNA, RNA protein sequence has immense biological signi cance. The characterization and recognition of motifs is therefore an important method for a more in-depth understanding ... -
Identifying the best metrics to find the best quality clusters of genes from gene expression data
(Brac University, 2019-04)Microarray data is used to create groups of similar genes based on their phenotypic attributes. Information extracted from these groups of gene can be applied to path- way analysis, disease predictions, target identification ... -
In silico identification of molecular mimicry between T-cell epitopes of borrelia burgdorferi and the human proteome: implications for autoimmune response in Lyme disease
(Brac University, 2022-12)Autoimmune disorder is a dysfunctional immune system in a body, which attacks its own cells. Borrelia burgdorferi, a pathogenic bacterium, shares an intrinsic relation to Lyme disease in humans causing autoreactive responses ... -
Protein folding in HP model on hexagonal lattices with diagonals
(© 2014 BioMed Central Ltd., 2014)Three dimensional structure prediction of a protein from its amino acid sequence, known as protein folding, is one of the most studied computational problem in bioinformatics and computational biology. Since, this is a ... -
Qualitative classification of the breast cancer genome and clustering of the cancer gene network
(BRAC University, 2019-04)The purpose of cancer genome project is to classify the genetic variations that are related to clinical phenotypes. However, some studies showed that some specific cellular pathways are targeted by the cancer mutations ... -
Seqdev: an algorithm for constructing genetic elements using comparative assembly
(© 2016 Bangladesh Association for Plant Tissue, 2016)With the availability of recent next generation sequencing technologies and their low cost, genomes of different organisms are being sequenced frequently. Therefore, quick assembly of genome, transcriptome, and target ... -
Structural analysis of three pivotal SERK dependent PRR complexes of Arabidopsis thaliana
(Brac University, 2021-01)Pattern Triggered Immunity (PTI) is distinguished with the activities of pattern recognition receptors (PRRs), which play an essential role in plant defense mechanism. During aggression of microbes, PRRs immediately bind ...
