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    •   BracU IR
    • School of Pharmacy (PHR)
    • Bachelor of Pharmacy
    • Project report (Bachelor of Pharmacy)
    • View Item
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    Antihypertensive drugs and risk of cancer: A pharmacovigilance study

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    ID 13146064_PHR.pdf (725.0Kb)
    Date
    2017-08
    Publisher
    BRAC University
    Author
    Rahman, Ahadina
    Metadata
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    URI
    http://hdl.handle.net/10361/9336
    Abstract
    Antihypertensive drugs are widely used for the treatment of hypertension, heart failure and, recently, for cardiovascular risk reduction. Experimental studies implicate antihypertensive drugs in the regulation of cell proliferation, tumor progression and even cancer. The purpose of this study is to assess the association between cancer and previous use of antihypertensive medication, taking into account the class of antihypertensive drug and the occurrence of cancer between male and female. I took data of the signal from WHO Global Pharmacovigilance database named VigiBase and this database is available for general people by a web application VigiAccess. I use PRR and chi-square method to determine conduct my study. We select some antihypertensive drugs of several classes. This pharmacovigilance study suggests that all antihypertensive drugs are not associated with cancer. But some specific drugs of antihypertensive drugs which has large amount of reports has the risk of this association
    Keywords
    Antihypertensive drugs; Cancer; Pharmacovigilance study
     
    Description
    This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2017.
     
    Cataloged from PDF version of project report.
     
    Includes bibliographical references (page 64-69).
    Department
    Department of Pharmacy, BRAC University
    Collections
    • Project report (Bachelor of Pharmacy)

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