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    •   BracU IR
    • School of Pharmacy (PHR)
    • Bachelor of Pharmacy
    • Project report (Bachelor of Pharmacy)
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    Phytochemical and biological investigation of persicaria glabra

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    ID 12346001_PHR.pdf (1.011Mb)
    Date
    2017-07-09
    Publisher
    BRAC University
    Author
    Chakma, Utsha
    Metadata
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    URI
    http://hdl.handle.net/10361/9293
    Abstract
    Present study was performed to establish the scientific basis of the use of Persicaria glabra as one of the curing and therapeutic agents of traditional practices in Bangladesh. The methanolic extract of the leaves was subjected to in vitro biological investigation for antioxidant test (Total phenolic content and DPPH assay), antimicrobial test (Disc diffusion method) and cytotoxicity test (Brine shrimp lethality bioassay). The plant extract showed potent cytotoxic activity nearly equivalent to standard vincristine sulfate compound. The study also confirmed presence of good amount of total phenolic content and free radical scavenging activity by DPPH method. Antimicrobial screening also done by the extract but it showed low antimicrobial activity compared to standard antimicrobial agent (kanamycin). However, more investigation is needed to identify in vitro anticancer activity on human cell line for the justification of its traditional use for squamous cell carcinoma and high cytotoxic activity of the leaf extract.
    Keywords
    Phytochemical and biological; Persicaria glabra; Biological investigation
     
    Description
    This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2017.
     
    Cataloged from PDF version of project report.
     
    Includes bibliographical references (page 52-54).
    Department
    Department of Pharmacy, BRAC University
    Collections
    • Project report (Bachelor of Pharmacy)

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