• Login
    • Library Home
    View Item 
    •   BracU IR
    • Department of Pharmacy (PHR)
    • Bachelor of Pharmacy
    • Project report (Bachelor of Pharmacy)
    • View Item
    •   BracU IR
    • Department of Pharmacy (PHR)
    • Bachelor of Pharmacy
    • Project report (Bachelor of Pharmacy)
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    A study on aluminum toxicity with female rats: can vitamin E help to reduce its effect on biological systems?

    Thumbnail
    View/Open
    12146025_PHARMACY.pdf (1.813Mb)
    Date
    2016-02
    Publisher
    BRAC University
    Author
    Momtaz, Tanisha
    Metadata
    Show full item record
    URI
    http://hdl.handle.net/10361/7728
    Abstract
    Increasing complaints about metal toxicity have been reported with the modernization of medical science. However, in this field, aluminum has been a renewed matter of concern. Therefore, more impotence is given to find out natural as well as synthetic substances that can alleviate the toxic effect of aluminum in the body. That is why; this study has aimed to identify the effect of vitamin E in reducing the toxic effect on biological systems caused by Aluminum. The study was conducted for 28 days and with total 18 female albino Wistar rats weighing 138-150g. 18 rats were divided into three groups-control, aluminum treated and aluminum plus vitamin E treated. The control group was receiving normal drinking water along with two drops of Tween 80 whereas aluminum treated group was getting aluminum nitrate solution 1ml/rat containing half ‘x’ of body weight and two drops of Tween 80. Moreover, aluminum plus vitamin E treated group was receiving aluminum nitrate solution 1ml/rat containing half ‘x’ of body weight along with 1ml/rat vitamin containing 22.5 mg of vitamin E per kg and also two drops of Tween 80. After 28 days, the rats were sacrificed, and blood was collected from the heart using ventricular puncture method. The collected blood was sent for hematological and clinical bio-chemistry examinations. At the same time, the liver, skin, brain, kidney and ovary of the rats were collected in the formalin and sent for histopathological study. The clinical biochemistry examination showed significant results for all the parameters except basophils, while the histopathology showed that vitamin E has the potential to eliminate the toxic effects caused by aluminum.
    Keywords
    Aluminum toxicity; Female rats; Biological systems; Vitamin E
     
    Description
    This project report is submitted in a partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2016
     
    Cataloged from PDF version of project report.
     
    Includes bibliographical references (page 38-41).
    Department
    Department of Pharmacy, BRAC University
    Collections
    • Project report (Bachelor of Pharmacy)

    Copyright © 2008-2019 Ayesha Abed Library, Brac University 
    Contact Us | Send Feedback
     

     

    Policy Guidelines

    • BracU Policy
    • Publisher Policy

    Browse

    All of BracU Institutional RepositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Statistics

    View Usage Statistics

    Copyright © 2008-2019 Ayesha Abed Library, Brac University 
    Contact Us | Send Feedback