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dc.contributor.authorZahan, Ronok
dc.contributor.authorAli, Shaikh M Mohsin
dc.contributor.authorJesmin, Mele
dc.contributor.authorAzad, M Abul Kalam
dc.contributor.authorIslam, M Khairul
dc.identifier.citationAli, S. M. M., Jesmin, M., Azad, M. A. K., Islam, M. K., & Zahan, R. (2012). Anti-inflammatory and analgesic activities of acetophenone semicarbazone and benzophenone semicarbazone. Asian Pacific Journal of Tropical Biomedicine, 2(2 SUPPL.), S1036-S1039. doi:10.1016/S2221-1691(12)60357-8en_US
dc.descriptionThis article was published in Asian Pacific Journal of Tropical Biomedicine [© 2012 Asian Pacific Tropical Biomedical Magazine] and the definite version is available at : The article website is at:
dc.description.abstractTo study anti-inflammatory and analgesic activities in swiss albino mice, two schiff bases namely acetophenone semicarbazone (ASC) and benzophenone semicarbazone (BSC) were synthesized and characterized. Methods: Two doses of the test compounds 25 and 50 mg/kg (p.o) for each were selected throughout the research work. The anti-inflammatory activity of the test compounds was determined by 'carragenan induced mice paw edema inhibition' method. The analgesic activity was determined by both, 'acetic acid induced writhing' and 'tail immersion' methods. All such data were compared with standard drugs at the dose of 10 mg/kg (p.o.). Results: Both ASC and BSC have showed positive effects as anti-inflammatory and analgesic agents. Anti-inflammatory and analgesic activities of the test compounds at 50 mg/kg (p.o.) were quite comparable to those of standard drugs at 10 mg/kg (p.o.). Conclusion: Both ASC and BSC can be considered as potent anti-inflammatory and analgesic agents.en_US
dc.publisher© 2012 Asian Pacific Tropical Biomedical Magazine.en_US
dc.subjectAcetophenone semicarbazoneen_US
dc.subjectAnalgesic activityen_US
dc.subjectAnti-inflammatory activityen_US
dc.subjectBenzophenone semicarbazoneen_US
dc.subjectSchiff baseen_US
dc.titleAnti-inflammatory and analgesic activities of acetophenone semicarbazone and benzophenone semicarbazoneen_US
dc.contributor.departmentDepartment of Pharmacy, BRAC University

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