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    • Bachelor of Pharmacy
    • Project report (Bachelor of Pharmacy)
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    Phytochemical screening, membrane stabilizing activity and cytotoxicity of ethanol extract of swietenia mahagony leaf

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    Nadi Zohora.pdf (1.107Mb)
    Date
    2015-08
    Publisher
    BRAC University
    Author
    Nadi, Fatem-Tuz-Zohora
    Metadata
    Show full item record
    URI
    http://hdl.handle.net/10361/4662
    Abstract
    Swietenia mahagony is such a medicinal plant that has numerous significant properties. Different parts of this plant such as bark, stem, leaves, trunk, seed, fruit and flower exert medicinal efficiency that can be incorporated to treat diverse ailments and can develop new formulas essential to treat newer afflictions. Swietenia mahagony leaves were focused in this study which was extracted with ethanol as a solvent. In the current study, ethanol extract was subjected to phyto-chemical screening, membrane stabilizing activity as well as brine shrimp lethality bioassay. Phyto-chemical screening was done by using distinct reagents intended for identifying primary and secondary phyto-chemicals such as tannins, flavonoids, alkaloids, carbohydrates, glucosides, glycosides, saponins etc. It was found from the analysis that ethanol extract of Swietenia mahagony leaves contains carbohydrates, saponins and tannins primarily. From the membrane stabilizing assay, where acetyl alicylic acid which is a well-known anti-inflammatory drug was employed as reference standard reported to have minimum membrane stabilizing effect while incorporated with ethanol extract of leaves of Swietenia mahagony. In case of brine shrimp lethality bioassay, the ethanol extract showed satisfactory cytotoxic effect that permits more sophisticated assay to be executed in the future. To conclude, it can be claimed, the results obtained from the experimental data were appreciating enough to run further studies considering different parameters such as using different solvent type- methanol, ethanol, acetone, chloroform etc, activity of the plant extract on to evaluate anti-diabetic, anti-malarial effect etc
    Keywords
    Pharmacy; Phytochemical screening; Membrane stabilizing; Swietenia mahagony
     
    Description
    This project report is submitted in a partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2015
     
    Cataloged from PDF version of Internship report.
     
    Includes bibliographical references (page 51-53).
    Department
    Department of Pharmacy, BRAC University
    Collections
    • Project report (Bachelor of Pharmacy)

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