BRAF is one of the most vital serine/ threonine-protein kinase proto-oncogenes that performs a crucial role in cellular proliferation, growth, signaling and secretion. By deregulation of this gene can lead to terrible ...

Plants with antioxidant and cytotoxic activity possess wide number of different phytoconstituents such as tocopherol, polyphenolic compounds, flavonoids, ascorbic acid etc. However, plants having non-polyphenolic compounds ...

We are living in an era where the number of ageing population is increasing, as well as the demand for treating chronic conditions like cancer, cardiovascular disease, diabetes, etc. Considering the different types of ...

Lysosomal autophagy controls cellular homeostasis by degrading and recycling cytoplasmic molecules and organelles in the lysosome. This process in neuronal cells protects cognitive decline by removing abnormal intracellular ...

Prostate cancer is still a fatal disease at metastatic castration resistance stage (mCRPC) in spite of pursuing advancements in patient survival, indicating the necessity of therapeutic approaches. A significant number of ...

Among all the major cancer types, lung cancer is one of the most common as it holds a higher percentage of cancer related mortality and treating lung cancer is yet a challenge. Chemotherapy, radiation therapy, surgery ...

Nanotechnology is a new discipline meeting the requirement for novel methods in cancer treatment. Recently, cancer became very fatal condition that causes death worldwide. Hence, traditional cancer treatment like ...

Cancer is a very personalized disease which is why conventional oncology treatment following the ‘one size fits all’ method is unable to cure all patients effectively and for this, cancer remains one of the leading causes ...

Cancer is one of the leading causes of death worldwide. Traditional surgery or chemotherapy are not sufficient to remove cancer completely. Researchers are trying to find out individual pathways for targeting tumor niches ...

Nanoparticles have unique physicochemical and biological properties that make them one of the most promising candidate for targeted cancer therapy. Nanoparticle-based drug delivery has a number of advantages over conventional ...