• Login
    • Library Home
    View Item 
    •   BracU IR
    • School of Pharmacy (PHR)
    • Bachelor of Pharmacy
    • Project report (Bachelor of Pharmacy)
    • View Item
    •   BracU IR
    • School of Pharmacy (PHR)
    • Bachelor of Pharmacy
    • Project report (Bachelor of Pharmacy)
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Phytochemical and biological evaluation of methanolic extract of Boehmeria macrophylla leaves

    Thumbnail
    View/Open
    13146040_PHR.pdf (689.8Kb)
    Date
    2017-12
    Publisher
    BRAC University
    Author
    Tahmid, Tasin
    Metadata
    Show full item record
    URI
    http://hdl.handle.net/10361/11069
    Abstract
    The present study has been designed to test and establish the scientific basis of the use of Boehmeria macrophylla as potential therapeutic agent in traditional medicine in Bangladesh. The methanolic extract of leaves of Boehmeria macrophylla was chosen for phytochemical screening and in vitro biological evaluation for the first time. The preliminary phytochemical screening revealed the presence of carbohydrates, phenols, phytosterols, glycosides and saponin in the crude methanolic extract of the plant. The leaf extract showed noteworthy antioxidant activities through DPPH free radical scavenging assay, along with its total phenolic content, flavonoid content and antioxidant capacity. Moreover, moderate cytotoxic effect in brine shrimp lethality bioassay was also observed. Antimicrobial activity was evaluated by disc diffusion method and the result showed maximum activity against Bacillus subtilis. Increasing concentration of the methanolic extract may help establish its potential against other microorganisms. Additionally, thrombolytic activity was tested using Streptokinase which further presented the plant extract as a mild thrombolytic agent. Future investigations on this plant may help in the development of new drugs and also aid in the research of combination drugs to treat a wide variety of diseases in Bangladesh as well as around the world.
    Keywords
    Biological evaluation; Phytochemical evaluation; Boehmeria macrophylla
     
    Description
    This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018.
     
    Catalogued from PDF version of project report.
     
    Includes bibliographical references (page 40-42).
    Department
    Department of Pharmacy, BRAC University
    Collections
    • Project report (Bachelor of Pharmacy)

    Copyright © 2008-2019 Ayesha Abed Library, Brac University 
    Contact Us | Send Feedback
     

     

    Policy Guidelines

    • BracU Policy
    • Publisher Policy

    Browse

    All of BracU Institutional RepositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Statistics

    View Usage Statistics

    Copyright © 2008-2019 Ayesha Abed Library, Brac University 
    Contact Us | Send Feedback