Thesis (Master of Science in Biotechnology)
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Bioinformatics Analysis Reveals miR-98-5p as a potential Inhibitor of Tumor cell proliferation and metastasis in Colorectal Cancer by targeting the FZD3 receptor of the Wnt signaling pathway
(Brac University, 2021-12)According to the World Health Organization (WHO) report of 2020, Colorectal Cancer (CRC) is the third most common type of cancer and the second cause of cancer-related deaths in the world. However, the existing treatment, ... -
Comparative analysis of CRISPR-Cas systems of Yersinia pestis and Escherichia coli strains. (November 2020 – December 2021)
(Brac University, 2022-01)The CRISPR-Cas system primarily refers to the clustered regularly interspaced short palindromic repeats (CRISPR) and its related protein enzymes (Cas) that confer adaptive protection against bacteriophages and other exogenous ... -
Bio-sorption studies of chromium (VI) ions with modified chicken feathers
(Brac University, 2021-12)Adsorption is one of the most important methods for cleaning industrial waste effluents. Adsorbents such as activated carbon have been used for a long time to remove heavy metal ions from wastewater. However, such adsorbents' ... -
Study on the frequency of single nucleotide polymorphism (rs766432) in BCL11A gene and its association with hematological parameter and HbF level among HbE/β -thalassemia patients in Bangladeshi population
(Brac University, 2021-10)Background: Thalassemia is a genetic disorder that causes malformed globin chains in hemoglobin and is the most prevalent blood disorder worldwide with high incidence rates even in Bangladesh. When β-thalassemia is inherited ... -
Development of in-vitro bio-assay for The bioactivity determination of human Erythropoietin (rHuEPO) bio-pharmaceutical products (November 2020 - August 2021)
(Brac University, 2021-10)Erythropoietin is mainly secreted by the kidney and involved in the growth and maturation of erythroid cells from precursors (Jelkmann, et al, 2013). Insufficient production of EPO could result in anemia. Considering ... -
Bacterial biofilm significance and implication in the epidemiology of waterborne disease
(Brac University, 2021-09)In the epidemiology of WBDOs, assessing the possible risk of biofilm and studying it is crucial. In this study, we look at the epidemiology of waterborne diseases as well as the diseases altogether. WB disease outbreaks ... -
Vitamin D deficiency: characterization of an overlooked health hazard
(Brac University, 2020)Vitamin D or sunshine vitamin is a hormone precursor, soluble in fat and plays an important role in our body by participating in several endocrine autocrine and paracrine activities. Since it has many pleiotropic health ... -
Using synergic relation between bacteriophage and a bacterial species for checking the effects of antibiotic resistance genes on the lytic property of bacteriophages.
(Brac University, 2021)Bacterial transformation is a process of horizontal gene transfer (hgt) where a few bacteria pick up foreign genetic material from the environment. In terms of newer therapies being applied, antimicrobial resistance is ... -
Potential use of Vibriophage in association with antibiotic to treat the vibrio Cholerae biofilm
(Brac University, 2021-08)In cholera prevalent areas, Vibrio cholerae in the aqueous environment can exist in a cell aggregated form covered by an extra polysaccharide matrix called Biofilm. These type of cells are named as VBNC (viable but non ... -
Isolation, identification, and characterization of Streptomyces species from common scab lesions
(Brac University, 2020-06)Streptomyces scabiei is largely accepted as the causal organism of common scab on potato in Debiganj, Rangpur and other Streptomyces species associated with common scab are not often considered. This study, therefore, ... -
Structural analysis of three pivotal SERK dependent PRR complexes of Arabidopsis thaliana
(Brac University, 2021-01)Pattern Triggered Immunity (PTI) is distinguished with the activities of pattern recognition receptors (PRRs), which play an essential role in plant defense mechanism. During aggression of microbes, PRRs immediately bind ... -
Potato variety improvement through marker assisted selection
(Brac University, 2021-02)Late blight (LB), caused by Phytophthora infestans (Mont.) de Bary, is the most destructive for potato. The main objective of this study was to evaluate 72 potato lines, derived from cross products of the recipient cv. ... -
A comparative study of Environment Risk Assessment (ERA) guidelines of developing and developed countries including Bangladesh
(Brac University, 2021-05)Genetically Engineered (GE) plants are the demand of time for increased demand of food. According to the report of International Service for the Acquisition of Agri-biotech Applications (ISAAA), a total of 29 countries ... -
Structural dynamics of PRR FLS2, PAMP flg22 and mutated co-receptor BAK1 of Arabidopsis thaliana
(Brac University, 2021-03)Pattern-triggered immunity (PTI) acts as the first layer of defense that is deployed by plants in order to avert microbial invasions. It is actually identified by the activities of patternrecognition receptors (PRRs), ... -
In-hospital outcome of Diabetes patients with Chronic Kidney Disease
(Brac University, 2021-03)Chronic Kidney Disease is a risk factor for cardiovascular event- Angina, Myocardial Infarction, Arrhythmia, Diabetes and In-hospital complication. Several studies have been done to find out association of Chronic Kidney ... -
Overview of the risk factors, prevention and management of SARS-COV-2
(Brac University, 2020-08)SARS-CoV-2, the novel corona virus that originated in Wuhan, China in late December is a positive single stranded RNA virus. COVID-19, a disease caused by the SARS-CoV-2 is characterized by symptoms such as fever, sore ... -
Can phages be cheated? - A study on the influence of inducing molecules on bacteriophage propagation at low host cell densities
(Brac University, 2020-06)It has been reported in vitro that bacteriophages require a certain host cell density in order to propagate. However, previous studies have shown that in environment, especially in water bodies, bacteriophage infection ... -
Detection of antibiotic resistance spectrum and resistance genes for aminoglycoside, macrolide, and β-lactam antibiotics using wound swab samples
(Brac University, 2020-01)Antibiotic resistance has become a global health problem with a decrease in efficacy in treating common infections, resulting in increased sufferings, duration of hospital stay and economic burden. Infections in the wound ... -
Effect of D122N mutation in BAK1 on structural integrity of protein complex consisting FLS2, flg22 and BAK1 ectodomain- a molecular dynamics study”
(Brac University, 2020-01)Elongated (elg) phenotype of Arabidopsis thaliana is caused by D122N mutation in the third leucine repeat of BRI1-associated kinase 1 (BAK1) protein that changes the 122nd amino acid aspartate to asparagine. The mutation ... -
Pathway analysis of Disease-Gene associated network in the human breast cancer
(Brac University, 2020-01)The research of human genes and diseases is very interrelated and can lead to an improvement in healthcare, disease diagnostics, and drug discovery. In this work, a system was established to construct similarity measures ...
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