Thesis (Master of Science in Biotechnology)
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Potato variety improvement through marker assisted selection
(Brac University, 2021-02)Late blight (LB), caused by Phytophthora infestans (Mont.) de Bary, is the most destructive for potato. The main objective of this study was to evaluate 72 potato lines, derived from cross products of the recipient cv. ... -
A comparative study of Environment Risk Assessment (ERA) guidelines of developing and developed countries including Bangladesh
(Brac University, 2021-05)Genetically Engineered (GE) plants are the demand of time for increased demand of food. According to the report of International Service for the Acquisition of Agri-biotech Applications (ISAAA), a total of 29 countries ... -
Structural dynamics of PRR FLS2, PAMP flg22 and mutated co-receptor BAK1 of Arabidopsis thaliana
(Brac University, 2021-03)Pattern-triggered immunity (PTI) acts as the first layer of defense that is deployed by plants in order to avert microbial invasions. It is actually identified by the activities of patternrecognition receptors (PRRs), ... -
In-hospital outcome of Diabetes patients with Chronic Kidney Disease
(Brac University, 2021-03)Chronic Kidney Disease is a risk factor for cardiovascular event- Angina, Myocardial Infarction, Arrhythmia, Diabetes and In-hospital complication. Several studies have been done to find out association of Chronic Kidney ... -
Overview of the risk factors, prevention and management of SARS-COV-2
(Brac University, 2020-08)SARS-CoV-2, the novel corona virus that originated in Wuhan, China in late December is a positive single stranded RNA virus. COVID-19, a disease caused by the SARS-CoV-2 is characterized by symptoms such as fever, sore ... -
Can phages be cheated? - A study on the influence of inducing molecules on bacteriophage propagation at low host cell densities
(Brac University, 2020-06)It has been reported in vitro that bacteriophages require a certain host cell density in order to propagate. However, previous studies have shown that in environment, especially in water bodies, bacteriophage infection ... -
Detection of antibiotic resistance spectrum and resistance genes for aminoglycoside, macrolide, and β-lactam antibiotics using wound swab samples
(Brac University, 2020-01)Antibiotic resistance has become a global health problem with a decrease in efficacy in treating common infections, resulting in increased sufferings, duration of hospital stay and economic burden. Infections in the wound ... -
Effect of D122N mutation in BAK1 on structural integrity of protein complex consisting FLS2, flg22 and BAK1 ectodomain- a molecular dynamics study”
(Brac University, 2020-01)Elongated (elg) phenotype of Arabidopsis thaliana is caused by D122N mutation in the third leucine repeat of BRI1-associated kinase 1 (BAK1) protein that changes the 122nd amino acid aspartate to asparagine. The mutation ... -
Pathway analysis of Disease-Gene associated network in the human breast cancer
(Brac University, 2020-01)The research of human genes and diseases is very interrelated and can lead to an improvement in healthcare, disease diagnostics, and drug discovery. In this work, a system was established to construct similarity measures ... -
An investigation of Mobilized Colistin-Resistance (MCR) gene and underlying dissemination mechanism using clinical, poultry and environmental samples in Bangladesh
(Brac University, 2020-01)Colistin, widely considered as the last-resort antibiotic for the treatment against multidrug-resistant (MDR) gram-negative bacteria worldwide, is being used indiscriminately in the poultry, livestock and fishery farms ... -
A study to investigate the correlation of abundance between the spacers and the prophages in bacterial genome
(Brac University, 2019-09)Bacteriophages, the most abundant and diverse entities in the biosphere which are composed of a nucleic acid molecule that is surrounded by a protein structure. These viruses can infect or kill bacteria through lytic and ... -
Evaluation of the antioxidant and in vivo anticancer activity of Excoecaria agallocha bark extract
(Brac University, 2019-10)Mangrove ecosystems have been known to possess diverse secondary metabolites and a good number of bioactive compounds of pharmaceutical importance have been reported from the mangrove plants. Mangrove plants are biochemically ... -
Mutation patterns in the HBB gene determine the frequency and onset of blood transfusion in patients with beta-thalassemia major and HbE-beta thalassemia
(Brac University, 2019-11)Thalassemia is a blood disorder passed down through families (inherited) in which the body makes an abnormal form or inadequate amount of hemoglobin. Co-inheritance of beta-thalassemia alleles from two parents results ... -
Prospects of Biodegradable Polymer (Polyhydroxyalkanoate) production with wastewater
(Brac University, 2019-10)Plastic production and accumulation have devastating environmental effects, and consequently, the world is in need to focus on environmentally friendly plastic substitutes such as sustainable biofuels, biomaterials, and ... -
A study on the effect of genome size on the multiplication rate of bacteriophages
(Brac University, 2019-09)Bacteriophages encapsidated by a protein coat have the competency of infecting bacteria, are the most abundant living entities on earth whose genome in general falls into three size ranges and 30-50kbp genetic material ... -
Quorum regulated resistance of E. coli against environmental bacteriophages
(Brac University, 2019-09)Predation of bacteria by their corresponding phages have a significant influence on the population structure of different communities of bacteria. E. coli infection has become a safety concern globally and they are causing ... -
Investigation of insulin promoter factor 1 gene C18R and R197H variants association with type 2 diabetes mellitus in Bangladeshi population
(Brac University, 2019-07)Diabetes Mellitus (DM) is a common metabolic disorder, resulting from defects in insulin secretion, insulin action, or both. But the molecular mechanism behind the basic defects of DM is not yet fully understood. Defect ... -
Detection of beta globin gene mutations in thalassemia patients in Bangladesh and correlation with hematological parameters
(Brac University, 2018-12)β-thalassemia and hemoglobin E (Hb E) diseases are highly prevalent autosomal recessive disorders characterized by the reduced or absent expression of the β globin gene. β-thalassemia is now regarded as the most common ... -
Multi-hospital surveillance and antibiotic sensitivity among bacterial isolates of acute respiratory and enteric infection in underfive children in Dhaka, Bangladesh
(BRAC University, 2015-07-27)Acute lower respiratory tract infection (ARI), enteric fever and diarrhea remain the prevalent causes for mortality and morbidity of under-five children in Bangladesh. However, little information is available on true ... -
In silico modelling and structural dynamics of PRR CORE ectodomain and its interaction with PAMP csp22
(BRAC University, 2018-11)Plants being sessile organisms are continuously being subjected to pathogens prevailing in their environment. Understanding the theory behind it would be a great step towards understanding the mechanisms making plants ...
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