Thesis (Master of Science in Biotechnology)
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Recent Submissions
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Pathway analysis of Disease-Gene associated network in the human breast cancer
(Brac University, 2020-01)The research of human genes and diseases is very interrelated and can lead to an improvement in healthcare, disease diagnostics, and drug discovery. In this work, a system was established to construct similarity measures ... -
An investigation of Mobilized Colistin-Resistance (MCR) gene and underlying dissemination mechanism using clinical, poultry and environmental samples in Bangladesh
(Brac University, 2020-01)Colistin, widely considered as the last-resort antibiotic for the treatment against multidrug-resistant (MDR) gram-negative bacteria worldwide, is being used indiscriminately in the poultry, livestock and fishery farms ... -
A study to investigate the correlation of abundance between the spacers and the prophages in bacterial genome
(Brac University, 2019-09)Bacteriophages, the most abundant and diverse entities in the biosphere which are composed of a nucleic acid molecule that is surrounded by a protein structure. These viruses can infect or kill bacteria through lytic and ... -
Evaluation of the antioxidant and in vivo anticancer activity of Excoecaria agallocha bark extract
(Brac University, 2019-10)Mangrove ecosystems have been known to possess diverse secondary metabolites and a good number of bioactive compounds of pharmaceutical importance have been reported from the mangrove plants. Mangrove plants are biochemically ... -
Mutation patterns in the HBB gene determine the frequency and onset of blood transfusion in patients with beta-thalassemia major and HbE-beta thalassemia
(Brac University, 2019-11)Thalassemia is a blood disorder passed down through families (inherited) in which the body makes an abnormal form or inadequate amount of hemoglobin. Co-inheritance of beta-thalassemia alleles from two parents results ... -
Prospects of Biodegradable Polymer (Polyhydroxyalkanoate) production with wastewater
(Brac University, 2019-10)Plastic production and accumulation have devastating environmental effects, and consequently, the world is in need to focus on environmentally friendly plastic substitutes such as sustainable biofuels, biomaterials, and ... -
A study on the effect of genome size on the multiplication rate of bacteriophages
(Brac University, 2019-09)Bacteriophages encapsidated by a protein coat have the competency of infecting bacteria, are the most abundant living entities on earth whose genome in general falls into three size ranges and 30-50kbp genetic material ... -
Quorum regulated resistance of E. coli against environmental bacteriophages
(Brac University, 2019-09)Predation of bacteria by their corresponding phages have a significant influence on the population structure of different communities of bacteria. E. coli infection has become a safety concern globally and they are causing ... -
Investigation of insulin promoter factor 1 gene C18R and R197H variants association with type 2 diabetes mellitus in Bangladeshi population
(Brac University, 2019-07)Diabetes Mellitus (DM) is a common metabolic disorder, resulting from defects in insulin secretion, insulin action, or both. But the molecular mechanism behind the basic defects of DM is not yet fully understood. Defect ... -
Detection of beta globin gene mutations in thalassemia patients in Bangladesh and correlation with hematological parameters
(Brac University, 2018-12)β-thalassemia and hemoglobin E (Hb E) diseases are highly prevalent autosomal recessive disorders characterized by the reduced or absent expression of the β globin gene. β-thalassemia is now regarded as the most common ... -
Multi-hospital surveillance and antibiotic sensitivity among bacterial isolates of acute respiratory and enteric infection in underfive children in Dhaka, Bangladesh
(BRAC University, 2015-07-27)Acute lower respiratory tract infection (ARI), enteric fever and diarrhea remain the prevalent causes for mortality and morbidity of under-five children in Bangladesh. However, little information is available on true ... -
In silico modelling and structural dynamics of PRR CORE ectodomain and its interaction with PAMP csp22
(BRAC University, 2018-11)Plants being sessile organisms are continuously being subjected to pathogens prevailing in their environment. Understanding the theory behind it would be a great step towards understanding the mechanisms making plants ... -
A study on hematological parameters of tuberculosis patients in Bangladesh
(BRAC University, 2018-11)Among all the infectious diseases, tuberculosis (TB) remains the deadliest. In 2017, the World Health Organization (WHO) ranked Bangladesh 6th among the world’s 22 high-burden TB countries. In this study various hematological ... -
Molecular and phenotypic investigations of enzyme mediated resistance profiles against aminoglycoside antibiotics in gram-negative clinical isolates in Dhaka, Bangladesh
(BRAC University, 2018-09)In recent decades, focus has shifted from notorious Gram-positive pathogens to Gram-negative threats, the majority of which comprise members of the Enterobacteriaceae and Pseudomonadaceae families. These, often commensal ... -
Effect of physical parameters on the decolorization of multiple synthetic textile dyes by bacteria recovered from dye contaminated soil and water
(BRAC University, 2018-07)Textile wastewater is a complex mixture of many contaminating materials. These include a high concentration of salts, acids, heavy metals, organochlorine-based pesticides, pigments, dyes etc. Dye is the first pollutant ... -
Degradation of dyes used in textile Industries by bacteria isolated from local textile effluents
(BRAC University, 2017-06)The effluent discharges from textile processing industries contain a significant amount of unreacted dyes. Release of these dyes into the environment causes toxic effects to the environment. The application of microorganisms ... -
Isolation of cellulolytic bacteria from soil sample and production of cellulase and its purification
(BRAC Univeristy, 2018-03)The cellulase producing bacteria were isolated from cow dung and characterized by morphological and biochemical analysis. Hence, studies pursue to unfold a novel cellulase that can overcome existing challenges in biorefinery, ... -
In vivo propagation of monoclonal antibodies in ascites fluid produced in BALB/c mice: characterization and diagnostic application for the identification of Vibrio cholerae O1
(BRAC University, 2017-07)Monoclonal antibodies are powerful tools in biomedical sciences. High affinity of binding domains of monoclonal antibodies towards a specific antigen enables their use in diagnostic assays and kits to identify particular ... -
Behaviour of gut bacteria upon stress in infants with ileostomy due to Hirschsprung disease
(BRAC University, 2017-06)Hirschsprung disease (HD) is a congenital one where the distal part of intestine lacks nerve ganglions, resulting in failure of defecation through anus. As treatment purpose, a stoma is created temporarily in the abdomen. ... -
Prevalence and molecular characterization of extended spectrum Beta-Lactamase producing multidrug-resistant Pseudomonas aeruginosa and Klebsiella pneumoniae isolates
(2017-06)The discovery of antibiotics has revolutionized health care worldwide. However, the life-saving role of antibiotics is threatened by the emergence of antibiotic- resistant ‘superbugs’. With the emergence of antibiotic ...
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