Analysis of the antibacterial and thrombolytic activity of citrus sinensis peel extracts

Abstract

Citrus sinensis (C. sinensis) has been traditionally used for the diagnosis of many diseases which includes- asthma, hypertension, microbial infections, diabetes, tuberculosis, etc. It contains many types of phytochemicals such as flavonoids, saponinss, tannins, glycosides, limonene, citral, neohesperidin, naringin, rutin, rhamnose, eriocitrin, and vitamin C. These phytonutrients may go about as cancer prevention agents, animate the invulnerable frameworks; prompt defensive proteins in the liver or square the harm of the hereditary materials. C. sinensis showed antimicrobial activity against many micro-organisms which can be taken into account for the treatment of infectious diseases. In this research some of the bacteria which are responsible for gastrointestinal order have been taken into consideration and the antibacterial activity of C. sinensis was studied with them. The Studied bacterial strains are Pseudomonas aeruginosa, Bacillus cereus and Klebsiella sp. The different concentrations of the sample have been used to evaluate the antimicrobial activity of methanolic peel extracts of C. sinensis. It provides antimicrobial activity against these micro-organisms with the increase of sample’s concentration. There was no research done for the thrombolytic activity of the C. sinensis peel extracts before. Thrombolysis is also referred as clot bursting. Thrombolysis causes disruption in normal blood flow. Methanolic peel extracts of C. sinensis show weak thrombolytic activity, but the data can be used for further study. Researchers might use other techniques to reveal thrombolytic activity which can be used for the diagnosis of patients and as it is an herbal drug it would have negligible side effects, adding a preferable treatment for the patients.